Eye Drops (Capacity: 24000 Bottles/Day)

EYE DROPS

[EIRI/EDPR/4681] J.C.: 2898XL

Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Eye drops usually contain saline to match the salinity of the eye. Drops containing only saline and sometimes a lubricant are often used as artificial tears to treat dry eyes or simple eye irritation such as itching or redness. Eye drops may also contain one or more medications to treat a wide variety of eye diseases. Depending on the condition being treated, they may contain steroids, antihistamines, sympathomimetics, beta receptor blockers, parasympathomimetics, parasympatholytics, prostaglandins, nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, antifungals, or topical anesthetics.

Eye drops have less of a risk of side effects than do oral medicines, and such risk can be minimized by occluding the lacrimal punctum (i.e. pressing on the inner corner of the eye) for a short while after instilling drops.

Prior to the development of single-use pre-loaded sterile plastic applicators, eye drops were administered using an eye dropper, a glass pipette with a rubber bulb.

Although most bottles of eye drops contain preservatives to inhibit contamination once opened, these will not prevent contamination indefinitely. Ophthalmologists recommend keeping bottles for no longer than three months after opening.[1] Eye drops that contain no preservatives are usually packaged in single-use tubes. Dispensers typically oversize the drops; the human eye can only handle about 25 microlitres.

COST ESTIMATION

Plant Capacity            24000 Bottles/Day

Land & Building (3000 sq.mt.)    Rs. 4.98 Cr

Plant & Machinery                    Rs. 1.70 Cr

Working Capital for 2 Months    Rs. 1.29 Cr

Total Capital Investment          Rs. 8.36 Cr

Rate of Return                          28%

Break Even Point                      57%

CONTENTS

INTRODUCTION

TYPES & USES OF EYE DROPS

STEROID AND ANTIBIOTIC EYE DROPS

PINK EYE

ALLERGIES

GLAUCOMA

MYDRIATIC EYE DROPS

EYE DROP PREPARATION

IN GENERAL, EYE DROPS ARE PREPARED IN ONE OF TWO WAYS:

1. STERILISATION

THE OPTIONS ARE:

AUTOCLAVING:

FILTER STERILIZATION:

2. INHERENT TOXICITY OF THE DRUG

3. REMOVAL OF PARTICULATES

4. PH

5. TONICITY

6. PRESERVATIVES

7. STABILITY

8. PACKAGING AND STORAGE OF THE FINAL PRODUCT

MARKET OVERVIEW OF EYE DROPS

HOW IS LACK OF AWARENESS AFFECTING GROWTH?

HOW BIG IS THE OPPORTUNITY IN THE UNITED STATES?

HOW IS THE OPHTHALMIC EYE DROPS MARKET IN GERMANY

FLOURISHING?

HOW IS THE OPHTHALMIC EYE DROPS SECTOR PERFORMING IN JAPAN?

WHAT IS THE FUTURE OUTLOOK FOR THE UNITED KINGDOM'S

OPHTHALMIC EYE DROPS INDUSTRY?

WHAT ARE THE CURRENT TRENDS IN THE OPHTHALMIC EYE

DROPS INDUSTRY IN CHINA?

WHAT ARE THE FACTORS DRIVING THE INDIA OPHTHALMIC EYE

DROPS INDUSTRY?

WHY DO STEROID EYE DROPS DOMINATE THE OPHTHALMIC EYE

DROPS MARKET?

FORMULATION OF EYE DROP PREPARATION

AUTOMATIC PRODUCTION LINE OF ASEPTIC EYE DROPS

IN SHORT, THE ASEPTIC FILLING PROCESS INVOLVES:

WHICH PACKAGING CONTAINER DO ASEPTIC FILLING MACHINES USE?

WHICH TYPES OF ASEPTIC FILLING PHARMACEUTICAL MACHINES ARE THERE?

1) ASEPTIC VIAL FILLING MACHINE

2) ASEPTIC BOTTLE FILLING MACHINE

3) ASEPTIC AMPOULE FILLING MACHINE

4) ASEPTIC EYE DROP FILLING MACHINE

PRINCIPLES OF PLANT LAYOUT

STORAGE LAYOUT:

EQUIPMENT LAYOUT:

SAFETY:

PLANT EXPANSION:

FLOOR SPACE:

UTILITIES SERVICING:

BUILDING:

MATERIAL-HANDLING EQUIPMENT:

RAILROADS AND ROADS:

MAJOR PROVISIONS IN ROAD PLANNING FOR MULTIPURPOSE SERVICE ARE:

PLANT LOCATION FACTORS

PRIMARY FACTORS

1. RAW-MATERIAL SUPPLY:

2. MARKETS:

3. POWER AND FUEL SUPPLY:

4. WATER SUPPLY:

5. CLIMATE:

SPECIFIC FACTORS

6. TRANSPORTATION:

A. AVAILABILITY OF VARIOUS SERVICES AND PROJECTED RATES

7. WASTE DISPOSAL:

8. LABOR:

9. REGULATORY LAWS:

10. TAXES:

11. SITE CHARACTERISTICS:

12. COMMUNITY FACTORS:

13. VULNERABILITY TO WARTIME ATTACK:

14. FLOOD AND FIRE CONTROL:

EXPLANATION OF TERMS USED IN THE PROJECT REPORT

1. DEPRECIATION:

2. FIXED ASSETS:

3. WORKING CAPITAL:

4. BREAK-EVEN POINT:

5. OTHER FIXED EXPENSES:

6. MARGIN MONEY:

7. TOTAL LOAD:

8. LAND AREA/MAN POWER RATIO:

PROJECT IMPLEMENTATION SCHEDULES

INTRODUCTION

PROJECT HANDLING

PROJECT SCHEDULING

PROJECT CONSTRUCTION SCHEDULE

TIME SCHEDULE

ADDRESSES OF RAW MATERIAL SUPPLIERS

ADDRESSES OF PLANT AND MACHINERY SUPPLIERS

PLANT LAYOUT

APPENDIX – A:

01. PLANT ECONOMICS

02. LAND & BUILDING

03. PLANT AND MACHINERY

04. OTHER FIXED ASSESTS

05. FIXED CAPITAL

06. RAW MATERIAL

07. SALARY AND WAGES

08. UTILITIES AND OVERHEADS

09. TOTAL WORKING CAPITAL

10. TOTAL CAPITAL INVESTMENT

11. COST OF PRODUCTION

12. TURN OVER/ANNUM

13. BREAK EVEN POINT

14. RESOURCES FOR FINANCE

15. INSTALMENT PAYABLE IN 5 YEARS

16. DEPRECIATION CHART FOR 5 YEARS

17. PROFIT ANALYSIS FOR 5 YEARS

18. PROJECTED BALANCE SHEET FOR (5 YEARS)