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    Detailed Project Report on i.v. fluid unit (ringer's lactate, normal saline, dextrose 4.3%, 5%, 10%, 50% & darrows solution)

    Detailed Project Report on i.v. fluid unit (ringer's lactate, normal saline, dextrose 4.3%, 5%, 10%, 50% & darrows solution)
    Detailed Project Report on i.v. fluid unit (ringer's lactate, normal saline, dextrose 4.3%, 5%, 10%, 50% & darrows solution)
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      I.V. FLUID UNIT
      (Ringer's Lactate, Normal saline, Dextrose 4.3%, 5%, 10%, 50% & Darrows solution)
      [CODE NO.3943]  
       
      Intravenous fluids, also known as intravenous solutions, are supplemental fluids used in intravenous therapy to restore or maintain normal fluid volume and electrolyte balance when the oral route is not possible. 
      IV fluid therapy is an efficient and effective way of supplying fluids directly into the intravascular fluid compartment, in replacing electrolyte losses, and in administering medications and blood products.
      STANDARD IVF & ELECTROLITES
       
      - NaCl 0,18 – 2.7%
       
      - Glucose 2,5 - 50%
       
      - Sodium Lactate (Hartmanns’s) Solution
       
      - Ringer Lactate
       
      - Water For injection
       
      - Sterile Water for Irrigation
       
      - Sodium Chloride 0.9% for irrigation
       
      - Sodium Chloride 0.18 – 0.45% and Glucose 4 – 10 %
       
      - Potassium Chloride  0.15 – 0.3% in Sodium Chloride 0.9%
       
      - Potassium Chloride  0.15 – 0.3% in Glucose 5%
       
       
       
      COST ESTIMATION
       
      Plant Capacity            48000 Pcs/Day  
      Land & Building (2000 sq.mt.)  US$ 4.52 Lac    
      Plant & Machinery               US$ 2.60 Lac 
      Working Capital for 1 Month    US$ 3.19 Lac 
      Total Capital Investment        US$ 10.73 Lac 
      Rate of Return                  50%
      Break Even Point                74%
       
       
       
      INTRODUCTION
      STANDARD IVF & ELECTROLITES
      THE AIMS OF IV FLUID ADMINISTRATION SHOULD BE TO
      BASIC IV SETUP
      TYPES OF IV FLUIDS
      IV SOLUTIONS CAN ALSO BE CLASSIFIED BASED ON THEIR PURPOSE
      CRYSTALLOIDS
      ISOTONIC IV FLUIDS
      0.9% NACL (NORMAL SALINE SOLUTION, NSS)
      DEXTROSE 5% IN WATER (D5W)
      LACTATED RINGER’S 5% DEXTROSE IN WATER (D5LRS)
      RINGER’S SOLUTION
      HYPOTONIC IV FLUIDS
      0.45% SODIUM CHLORIDE (0.45% NACL)
      0.33% SODIUM CHLORIDE (0.33% NACL)
      0.225% SODIUM CHLORIDE (0.225% NACL)
      2.5% DEXTROSE IN WATER (D2.5W)
      HYPERTONIC IV FLUIDS
      HYPERTONIC DEXTROSE SOLUTIONS
      DEXTROSE 10% IN WATER (D10W)
      DEXTROSE 20% IN WATER (D20W)
      DEXTROSE 50% IN WATER (D50W)
      NURSING CONSIDERATIONS FOR HYPERTONIC SOLUTIONS
      DARROW’S SOLUTION
      COLLOIDS
      HUMAN ALBUMIN
      DEXTRANS
      LOW-MOLECULAR-WEIGHT DEXTRANS (LMWD)
      HIGH-MOLECULAR-WEIGHT DEXTRANS (HMWD)
      IV FLUID/ELECTROLYTE THERAPY
      NORMAL SALINE
      VOLUME EFFECTS OF NS
      RINGER'S FLUIDS
      ADVANTAGE:
      DEXTROSE SOLUTIONS
      EFFECT OF DEXTROSE IN FLUID:
      VOLUME EFFECTS
      5 % DEXTROSE COMPOSITION:
      DEXTROSE SALINE (DNS)
      DEXTROSE WITH HALF STRENGTH SALINE
      HYPERTONIC SALINE • AVAILABLE AS 1.8%, 3%, 5%, AND 7.5%
      ISOLYTE G,M,P,E
      ECONOMIC PROFILE
      MARKET SURVEY
      APPLICATION INSIGHTS
      VOLUME INSIGHTS
      INDIA LARGE VOLUME PARENTERAL (LVP) MARKET SHARE INSIGHTS
      NORTH AMERICA AT THE FOREFRONT OF THE GLOBAL INTRAVENOUS 
          (IV) SOLUTION MARKET
      AFRICA’S PHARMACEUTICAL MARKET
      BUSINESS JUSTIFICATION
      PRODUCTS
      WHY NIGERIA?
      GLOBAL INTRAVENOUS SOLUTION MARKET: KEY TRENDS
      GLOBAL INTRAVENOUS SOLUTION MARKET: SEGMENTATION
      GLOBAL INTRAVENOUS SOLUTION MARKET: REGIONAL ANALYSIS
      GLOBAL INTRAVENOUS SOLUTION MARKET: COMPETITIVE LANDSCAPE
      MAJOR FIVE IV FLUID MONITORING DEVICES COMPANIES:
      B. BRAUN MELSUNGEN AG
      BAXTER INTERNATIONAL INC.
      BECTON, DICKINSON AND CO.
      FORTIVE CORP.
      ICU MEDICAL INC.
      SOURCE OF MACHINES TECHNOLOGY
      USES AND APPLICATION
      SOME GENERAL INTRAVENOUS FLUIDS
      SPECIFICATION OF INDIAN PHARMACOPEIA ON I.V FLUIDS DEXTRAN INJECTION
      DEXTRAN 110 INJECTIONS
      SODIUM CHLORIDE AND DEXTROSE INJECTION
      IDENTIFICATION:-
      ASSAY:
      BASIC RAW MATERIALS
      REQUIREMENTS OF RAW MATERIALS AND SPECIFICATIONS
      WATER FOR INJECTION
      HDPE PHARMA GRADE LAMINATE/ PLASTIC ROLL
      LABELING
      IDENTIFICATION
      HEAVY METALS
      COMPOSITION OF IV FLUID
      COMPOSITION OF COMMON IV FLUID (MEQ/L)
      COMPOSITION OF IV FLUIDS
      COMPOSITION OF COMMERCIAL I.V. FLUID AVAILABLE
      BASIS OF BFS TECHNOLOGY
      BLOW FILL SEAL EQUIPMENT
      BFS MOLDS AND TOOLING
      BFS TRIALS
      PROCESS
      1. BLOW MOLDING
      2. FILLING
      3. SEALING
      BLOW FILL SEAL MACHINES
      BLOW FILL SEAL IS SUITABLE FOR YOUR APPLICATION:
      ASEPTIC PACKAGING
      BLOW FILL SEAL (BFS) AND FORM FILL SEAL (FFS) TECHNOLOGY
      CONCEPT OF BFS
      MANUFACTURING PROCESS OF I.V. FLUID
      PROCESS IN DETAILS
      1. DISTILLED WATER PREPARATION:-
      2. SOLUTION PREPARATION:-
      3. INJECTION BLOW MOULDING
      4. MOULDING PROCESS
      5. FILLING PROCESS
      6. SEALING PROCESS
      7. MOULD OPENING PROCESS
      FILTRATION AND FILLING:-
      STERILIZATION:-
      QUALITY CONTROL:-
      THE WHOLE PROCESS CONSISTS OF THE FOLLOWING STEPS:-
      PROCESS FLOW DIAGRAM
      FLOW DIAGRAM OF MANUFACTURING OF I.V. FLUIDS
      FORM FILL SEAL TECHNOLOGY
      1. FORM-FILL-SEAL TECHNOLOGY:-
      1.3. TERMINALLY STERILIZED PRODUCTS.-
      1.5 FILTRATION (MEMBRANE):-
      1.7. STERILIZATION (BY DRY HEAT):-
      LIST OF MACHINERY IV BAG PRODUCTION FORM FILL AND SEAL MACHINE
      1.  WATER PURIFYING
      2.  DISTILLATION
      3.  SOLUTION FILLING
      4.  STERILIZATION
      5.  PACKING
      A TYPICAL FFS PROCESS WORKS AS FOLLOWS.
      SUPPLIERS OF RAW MATERIALS
      POTASSIUM PERMANGANATE
      SODIUM CHLORIDE (I.P. GRADE)
      DEXTROSE
      SUPPLIERS OF PLANT AND MACHINERY
      STERILIZING EQUIPMENTS
      PM METER
      LABELING MACHINES
      TANKS
      BOILER
      FILTER PRESS
      LABORATORY EQUIPMENTS
      MIXER
      MACHINERY PHOTOGRAPHS
      MULTIPLE EFFECT WATER DISTILLATION PLANT
      MIXER
      STORAGE VESSEL
      BLOW FILL SEAL MACHINE
      AUTOMATIC BOTTLE LABELLING MACHINES
      RAW MATERIAL SUPPLIER
      SODIUM LACTATE   
      NACL
      KCL       
      CACL2
      PRODUCT PHOTOGRAPHS
       
      APPENDIX – A:
       
      01. PLANT ECONOMICS
      02. LAND & BUILDING
      03. PLANT AND MACHINERY
      04. OTHER FIXED ASSESTS
      05. FIXED CAPITAL
      06. RAW MATERIAL
      07. SALARY AND WAGES
      08. UTILITIES AND OVERHEADS
      09. TOTAL WORKING CAPITAL
      10. TOTAL CAPITAL INVESTMENT
      11. COST OF PRODUCTION
      12. TURN OVER/ANNUM
      13. BREAK EVEN POINT
      14. RESOURCES FOR FINANCE
      15. INSTALMENT PAYABLE IN 5 YEARS
      16. DEPRECIATION CHART FOR 5 YEARS
      17. PROFIT ANALYSIS FOR 5 YEARS
      18. PROJECTED BALANCE SHEET FOR (5 YEARS)
       
       

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