Detailed Project Report on pharmaceutical unit tablet, capsules, syrups, lotion etc

PHARMACEUTICAL UNIT
TABLET, CAPSULES, SYRUPS, LOTION ETC.
[CODE NO.3749]  

The foundation of the modern Indian pharmaceutical Industry was laid at the start of the current century when in 1901, a small factory known as the Bengal Chemical & Pharmaceutical works was established in Kolkata. Though the two world Wars gave a Phillip to the development of industry, the progress made under British rule was not significant except the British introduced into this country the allopathic system of medicine. The country depended largely for its requirements on U.K., France and Germany.

The development of Indian Drugs and pharmaceuticals Industry was not commonsurate with the size of this country and the growing needs of people, when Indian embarked on its planned economic expansion industry has been substantial and many sides with the result that it has becomes one of the leading industries. India is now producing a larger quantity of varied pharmaceuticals products. In 1948, the sale of pharmaceuticals products. In 1948, the sale of pharmaceutical products amounted to just Rs. 100 million. By 1954 the figure had rised to Rs. 540 million and by 1960 to Rs. 700 million. The figure stood at between Rs. 1500 million in 1965 and Rs. 4000 millions in 1975, Rs. 12000 millions in 1980 and above Rs. 18,500 millions presently.

The restrictions, however, continued on import of non essential patent and proprietory medicen for which suitable substitutes manufactured indigenously were available.

Prior to the launching of the second plan the manufacture of pharmaceuticals was limited largely to the processing of bulk imported drugs into tablets, capsules and other formulations. Indian firms under agreement with foreign firms are making injectables, powders ointments and liquids, and were also filling antibiotics. Certain units were producing biological extracts, vacines, and syrup. Alkalods, like quinins stry-chinea, caffeine, and morphine were also being extracted. It was however obvious that the country could not forever be dependent on foreign manufacturers for both finished drugs and basis raw materials. With the changing political climate, pharmaceutical manufacturers in India were encouraged to take up the manufacture of basis drugs wherever it was economically possible and technically feasible.

A system of collaboration was instituted, under which Indian manufacturers in association with established firms in U.S.A., Italy, U.K. began to produce a fairly comprehensive range of basic items. While the allocation of foreign exchange for the import of raw materials and basic intermediates for the production  of drugs, has been more or less static the  value  of products  manufactured has increased progressively  several  fold clearly  indicating  the  growing stature, of  industry and its capacity to switching over to basic raw materials and  components of  indigenous origin, and now the country is stated  to  achieve self,  sufficiency in synthetic drugs of the sulpha  group, anti T.B. drugs, Vitamins, and intermediates.

It has, however, been found that the present installed capacity is insufficient to meet the over growing demand of the massive population and the scope for new units to come up is substantial.


COST ESTIMATION

Land & Building (0.25 Acre)      Rs. 40 Lac         
Plant & Machinery                      Rs. 57 Lac     
Working Capital for 2 Months     Rs. 58 Lac
Total Capital Investment              Rs. 1.66 Cr
Rate of Return            64%                   
Break Even Point             51%                


INTRODUCTION    
MARKET OVERVIEW OF PHARMACEUTICAL INDUSTRY    
GLOBAL MARKET DYNAMICS & IMPLICATIONS FOR INDIA PHARMA    
MULTIPLE DIGITAL AND ADVANCED ANALYTICS APPLICATIONS IN
   PHARMA VALUE CHAIN    
INDIA MARKET DYNAMICS & IMPLICATIONS FOR INDIA PHARMA    
INCREMENTAL GROWTH IN THE INDIAN PHARMACEUTICAL MARKET    
OPPORTUNITIES FOR INDIA AS A GLOBAL SUPPLY DESTINATION    
INSTITUTIONALIZING QUALITY AND COMPLIANCE EXCELLENCE    
BUILDING OPERATIONAL EXCELLENCE    
ALTERNATE SOURCING AND SELF-SUFFICIENCY IN APIS/INTERMEDIATES    
GLOBAL PHARMACEUTICAL MARKET    
PESTEL ANALYSIS FOR THE PHARMACEUTICALS MARKET    
PHARMACEUTICAL MARKET RESTRAINTS AND DRIVERS    
THE CHANGING GEOGRAPHY OF PHARMA MARKETS    
IN THE OVERALL MARKET, TOP PHARMACEUTICAL COMPANIES INCLUDE    
METHODS OF RAINWATER HARVESTING    
BROADLY THERE ARE TWO WAYS OF HARVESTING RAINWATER    
1. SURFACE RUNOFF HARVESTING    
2. ROOFTOP RAINWATER HARVESTING    
ROOFTOP RAINWATER HARVESTING SYSTEM    
COMPONENTS OF THE ROOFTOP RAINWATER HARVESTING    
THE SYSTEM MAINLY CONSTITUTES OF FOLLOWING SUB COMPONENTS    
CATCHMENTS    
TRANSPORTATION    
SAND GRAVEL FILTER    
CHARCOAL FILTER    
PVC –PIPE FILTER    
SPONGE FILTER    
METHODS OF ROOFTOP RAINWATER HARVESTING    
A) STORAGE OF DIRECT USE    
B) RECHARGING GROUNDWATER AQUIFERS    
C) RECHARGING OF BORE WELLS    
D) RECHARGE PITS    
E) SOAKWAY OR RECHARGE SHAFTS    
F) RECHARGING OF DUG WELLS    
G) RECHARGE TRENCHES    
H) PERCOLATION TANK    
MANUFACTURER OF PHARMACEUTICAL PRODUCTS    
FORMULATIONS OF TABLETS    
1.   TABLETS FOR FATIGUE & GENERAL TONIC    
2.   ANTI ASTHMATIC:-    
3.   COLCHICINE TABLETS    
5.   ANTI ALLERGIC TABLETS :    
6.   MULTI VITAMIN TABLETS, 500 MG EACH TABLET CONTAINS    
7.   ENTERO VIOFORM TABLETS:    
8.   TABLETS FOR COMMON COLD:    
9.   TABLETS FOR MENOAPUSE SYNDROMS:    
10.  STIMULATING TABLETS:    
11.  ANACIN TABLETS:    
12.  IRON TABLETS:    
13.  CAPSULES:    
14.  ANTI INFLAMMATORY ANTIPYRETIC AND ANALYGERIC:    
15. BROAD SPECTRUM ANIT-BIOTIC CASPULES:    
16.  IRON WITH VITAMIN CAPSULES:-    
17.  ANTI ANNEMIA CAPSULES:    
18.  CHLORAMPHENICOL CAPSULES:    
19.  HEAMATINIC CAPSULES:-    
20.  UROBIOTIC CAPSULES:    
INJECTIONS FORMULATIONS    
TERRAMYCIN 1 M :-    
AMPICILLIN INJECTION :-    
SULPHACETAMIDE EYE-DROP :-    
SULPHACETAMIDE EYE-DROP EACH ML CONTAINS:-    
BETENSOL-N-EYE/EAR DROPS CONTAINS:-    
SALIENT FEATURES OF FORMULATIONS OF DPHTHALMIC PREPARATIONS    
OXYTOCIN INJECTION:-    
OXYTOCIN -B VETC :-    
MANUFACTURING PROCESS OF INJECTIONS    
FILLING OF AMPOULES    
FORMULATIONS OF SYRUPS    
SYRUPS:    
ANTI ALLERGIC COUGH SYRUP:    
EDIATRIC SYRUP OF PARACETAMOL:    
VICKS FORMULA 44 COUGH MIXTURE    
PARACETAMOL - VITAMINIC SYRUP    
MULTIVITIMAN SYRUP    
COUGH SYRUP    
LIQUIDS:    
1.   GENERAL TONIC (MULTI VITAMIN)    
2.   SODIUM GLYCEROPHOSPHATE           
3.   VITAMIN B COMPLEX WITH DIGESTIVE ENZYMES:    
TONIC LIQUID:    
PALATABLE POTASSIUM SUPPLEMENT:    
1.   EYE LOTION:    
2.   SKIN LOTION (FOR SPOT & PIMPLES)    
3.   ANTI ALLERGIC LOTION (CALAMINE LOTION)    
TERRAMYCIN DENTAL PASTE:    
BEPARINE CREAM:    
ANTISEPTIC CREAM:    
ANTI FUNGAL SKIN OINTMENT:    
BURNOL OINTMENT:    
FORMULATION OF OINTMENT BASES:    
WASHABLE OINTMENT BASE (USED AS SCALP OINTMENT BASE)    
GREASE LESS BASE:  (USED IN MAKING SKIN OINTMENT)    
MANUFACTURING PROCESS (TABLETS)    
FLOW DIAGRAM OF TABLET MAKING PLANT    
MANUFACTURE OF LIQUIDS (SYRUP)    
FILTERATION:    
BOTTLING:    
FLOW DIAGRAM OF MIXING PLANT    
CAPSULE FILLING SEALING    
FILLING:    
SEALING AND LOCKING:    
FLOW DIAGRAM OF CAPSULE MAKING PLANT    
MANUFACTURE OF LOTION    
FLOW DIAGRAM OF LOTION MAKING PLANT    
OINTMENT AND PASTE MAKING    
FORMULATION:    
MACHINERY REQUIRED    
FLOW DIAGRAM FOR PASTE & OINTMENT MAKING    
SUPPLIERS OF PHARMACEUTICAL PLANTS MACHINERY    
SUPPLIERS OF RAW MATERIALS    
GELATINE    
FOOD COLOURS    
SODIUM SULPHATE    
PINE OIL    
GLYCERINE    
CAUSTIC SODA    
METHYLATED SPIRIT    
ASPIRIN    
PARACETAMOL TABLETS (PCM)    
PAPAIN POWDER    
VITAMIN    
THYMOL    

APPENDIX – A:

01.    PLANT ECONOMICS    
02.    LAND & BUILDING     
03.    PLANT AND MACHINERY    
04.    OTHER FIXED ASSESTS    
05.    FIXED CAPITAL    
06.    RAW MATERIAL    
07.    SALARY AND WAGES    
08.    UTILITIES AND OVERHEADS    
09.    TOTAL WORKING CAPITAL    
10.    TOTAL CAPITAL INVESTMENT    
11.    COST OF PRODUCTION    
12.    TURN OVER/ANNUM    
13.    BREAK EVEN POINT     
14.    RESOURCES FOR FINANCE    
15.    INSTALMENT PAYABLE IN 5 YEARS    
16.    DEPRECIATION CHART FOR 5 YEARS    
17.    PROFIT ANALYSIS FOR 5 YEARS    
18.    PROJECTED BALANCE SHEET FOR (5 YEARS)