Detailed Project Report on sterilization & packaging unit of latex gloves
Detailed Project Report on sterilization & packaging unit of latex gloves
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STERILIZATION & PACKAGING UNIT OF LATEX GLOVES
[CODE NO.3950]
Gloves are single-use items and should not be washed or reused. Polythene: Thin and have a tendency to tear. They are not an appropriate choice for healthcare settings. Vinyl: Have been shown to be less effective than latex gloves in providing an impermeable barrier against microorganisms.
Disposable medical gloves are available in nitrile, latex and vinyl materials. Any gloves worn by health professionals should be free of powder, sterile, textured and coated for extra protection. Nitrile tends to be the most favored glove material for those working in the healthcare industry.
A disposable glove is commonly made from natural or synthetic rubber that covers the whole hand and is used to protect the wearer against harmful environmental influences and/ or used by caregivers in health care to protect themselves and patients from infections. As the name implies, disposable gloves are designed for single use only and should be disposed immediately after use.
Sterilization:
It is a process by which an article, surface or medium is made free of all microorganisms either in vegetative or spore form. Ethylene oxide gas is commonly used to sterilize objects sensitive to temperatures greater than 60 °C and / or radiation such as plastics, optics and electrics. It can kill all known viruses, bacteria and fungi, including bacterial spores and is compatible with most materials (e.g. of medical devices), even when repeatedly applied. However, it is highly flammable, toxic and carcinogenic.
A typical process consists of a preconditioning phase, the actual sterilization run and a period of post-sterilization aeration to remove toxic residues, such as ethylene oxide residues.
COST ESTIMATION
Plant Capacity : 80000 Pcs/day
Land & Building (600 Sq.MT) : Rs. 44.99 Lacs
Plant & Machinery : Rs. 38.60 Lacs
Working Capital for 1 Month : Rs. 50.76 Lacs
Total Capital Investment : Rs. 1.43 Cr
Rate of Return : 54%
Break Even Point : 40%
INTRODUCTION
STERILIZATION:
HAND PROTECTION- ONE OF PPE’S
CHOICE OF GLOVES
PROJECT LOCATION-VADODARA
MAP OF DISTRICT
TRANSPORT
AIR
RAILWAY
ECONOMY
BRIEF HISTORY OF RUBBER
JOSEPH LISTER AND SURGICAL ASEPSIS
THE HISTORY OF DISPOSABLE GLOVES
1889
1894
1965
1992
MID-1990S
TODAY
TYPES OF DISPOSABLE GLOVES EXIST
USES & APPLICATION OF THIN NITRILE GLOVES
1) MEDICAL GLOVES
THE BASIC ELEMENTS OF EN455 ARE:
2) INDUSTRIAL, LABORATORY AND PHARMACEUTICAL GLOVES
3), WITH A CATEGORY 2 GLOVE WHICH DOES NOT FALL INTO THE CATEGORIES 1 OR 3.
MECHANICAL PROPERTIES
MECHANICAL PROPERTIES OF RUBBER LATEX GLOVE FILM AFTER DIPPING MOLD
TYPES OF GLOVES
GLOVE TYPES THE RUBBER GLOVES CAN BE DIVIDED BASICALLY INTO
4 DIFFERENT CATEGORIES,
MEDICAL GLOVES
MEDICAL GLOVES CAN FURTHER BE DIVIDED INTO TWO,
HOUSEHOLD GLOVES
INDUSTRIAL GLOVES
SPECIALITY GLOVES
EMERGENCY SERVICES
POLICE GLOVES
GLOVE PROPERTIES
THE PERFORMANCE REQUIREMENTS OF GLOVES ARE,
AFTER TREATMENTS OF GLOVES
CHLORINATION
POLYMER COATING
HYDROGEL COATINGS
LATEX IS KNOWN TO CAUSE TWO TYPES OF HYPERSENSITIVITY:
TYPE I ALLERGY
TYPE IV ALLERGY
"SAFE" PROTEIN LEVELS
POWDER-FREE GLOVES
TESTING AND QUALITY CONTROL OF GLOVES
IN-PROCESS TESTING
DIPPED LATEX PRODUCTS
WET-COACERVANT DIPPING
DRY-COACERVANT DIPPING ( COAGULANT DIPPING )
EXAMPLES OF DRY COACERVANT SOLUTIONS ARE GIVEN BELOW: PARTS
BY WEIGHT (PBW)
HEAT SENSITIZED DIPPING
ELECTRO DEPOSITION
FORMERS
DIPPING TANKS
DIPPING MACHINES
SEQUENCE OF OPERATIONS
GLOVE PRODUCTION & MANUFACTURING
THE GLOVES ARE MANUFACTURED BY EITHER A
BATCH DIPPING PROCESS
CONTINUOUS DIPPING PROCESS
LATEX DIPPING
LATEX CONCENTRATE
COMPOUNDING
COAGULANT DIPPING
LATEX DIPPING
BEADING
LEACHING
VULCANIZATION
POST LEACHING
SLURRY DIP
BEADING
LEACHING
VULCANIZATION
POST LEACHING
SLURRY DIP
STRIPPING
TUMBLING
GLOVE PACKING
GLOVE STERILIZATION
FINISHED GLOVES
ETHYLENE OXIDE STERILIZATION PROCESS
SIMPLE BUT EFFECTIVE
A SIMPLE EO PROCESS IN DETAIL
1. ENVIRONMENTAL PRECONDITIONING
ITEMS FOR CONSIDERATION:
2. INITIAL EVACUATION
TODAY, THE TWO MOST COMMON METHODS OF ACCOMPLISHING
THIS REQUIREMENT ARE
ITEMS FOR CONSIDERATION:
3. HUMIDIFICATION
4. GAS INJECTIONS AND GAS DWELL
ITEMS FOR CONSIDERATION:
5. POSTEXPOSURE GAS PURGE AND AIR INBLEED
6. HEATED AERATION
LATEX COMPOUND DESIGN FOR DIPPED GOODS
POLYMER:
FILLERS:
SOFTENERS:
STABILISERS:
ANTIOXIDANTS:
VISCOSITY MODIFIERS:
OTHER ADDITIVES
BRIEF ABOUT VULCANIZATION & ACCELERATORS
ACCELERATORS:
RAW MATERIAL
EXAMINATION GLOVES USED IN HEALTHCARE
ELEMENTS OTHER THAN THE GLOVE MATERIAL THAT DETERMINE
THE LEVEL OF BARRIER PROTECTION INCLUDE:
PROCESS FLOW DIAGRAM
FORMULATION
NR & NBR LATEX
ADVANTAGE & DISADVANTAGE
ADVANTAGE & DISADVANTAGE
THE QUALITY-CONTROL PHASE
MARKET SURVEY
PRODUCT SEGMENT
FORM SEGMENT REVIEW
KEY BENEFITS FOR INDIA DISPOSABLE GLOVES MARKET:
BY PRODUCT
BY FORM
BY APPLICATION
BY DISTRIBUTION CHANNEL
LAYOUT OF PHARMACEUTICAL BUILDING & SERVICES
STORAGE CONDITIONS
1. SHELF-LIFE DURATION OF STUDIES
2. EXPIRATION DATES
3. TEMPERATURE
4. ENVIRONMENTAL FACTORS
5. SPECIAL LABELING RESTRICTIONS
PHARMACEUTICAL PLANT LAYOUT
FEATURES OF A GOOD PHARMACEUTICAL PLANT LAYOUT
GOOD CGMP DESIGN FEATURES INCLUDE:
FLEXIBILITY:
MATERIALS OF CONSTRUCTION & SURFACE FINISHES
TYPICAL SEAMLESS EPOXY RESIN FLOORING SYSTEM
MATERIALS OF CONSTRUCTION & SURFACE FINISHES
CEILING SYSTEMS
CLEAN ROOM DOORS
STEEL DOORS
ELECTRIC SLIDING
GLAZING GLAZING
AIR SHOWERS
CLEAN ROOM PRESSURIZATION - EXAMPLE
MACHINERY SUPPLIERS
ETO UNIT
PACKAGING MACHINE
RAW MATERIAL SUPPLIERS
LATEX GLOVES
MACHINERY PHOTOGRAPHS
RAW MATERIAL PHOTOGRAPHS
LATEX GLOVES
EHYLENE OXIDE
APPENDIX – A:
1. COST OF PLANT ECONOMICS
2. LAND & BUILDING
3. PLANT AND MACHINERY
4. FIXED CAPITAL INVESTMENT
5. RAW MATERIAL
6. SALARY AND WAGES
7. UTILITIES AND OVERHEADS
8. TOTAL WORKING CAPITAL
9. COST OF PRODUCTION
10. PROFITABILITY ANALYSIS
11. BREAK EVEN POINT
12. RESOURCES OF FINANCE
13. INTEREST CHART
14. DEPRECIATION CHART
15. CASH FLOW STATEMENT
16. PROJECTED BALANCE SHEET
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