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    Detailed Project Report on Surgical Methylated Spirit

    Detailed Project Report on Surgical Methylated Spirit
    Detailed Project Report on Surgical Methylated Spirit
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      SURGICAL METHYLATED SPIRIT
      [EIRI/EDPR/1619] J.C.: 422


      INTRODUCTION

      The most widely used antiseptics and disinfectants are alcohols, chlorine containing compounds, elemental and organic iodine preparations, inorganic and organic mercurials, inorganic and organic preparations of silver, quaternary ammonium compounds, phenolic compounds, boric acid and other borates, oxidising agents and aldehyde derivatives. The aliphatic alcohols have varying degrees of antiseptic and disinfecting activity. Those most widely used are ethyl and isopropyl alcohol. Normal propyl alcohol has considerable bactericidal activity but is seldom used as an antiseptic. Methyl alcohol has no place in antiseptics. Benzyl alcohol is present as a bacteriostatic agent in a number of parenteral preparations. Alcohols are applied to the skin to reduce local bacterial flora prior to penetration with needles or other sharp instruments and as a preoperative wash. The disinfecting action of alcohol can be enhenced to a considerable degree by gentle rubbing of the skin with sterile gauge, while the alcohol is being  applied. Ethyl alcohol is the most widely used agent for disinfection of the skin and is one of the better bactericides because it acts rapidly by coagulating protein. The 70% aqueous solution is more effective in reducing the surface tension of bactorial cells than undiluted alcohol which precipitates protoplasm on the priphery of the cell and thus tends to retard penetration of the agent. In surgery the skin is cleaned with a nonflammable defatting agent prior to applications of alcohol. Ethyl alcohol is not sporicidal in any concentration, therefore it is not useful for sterilization of instruments. This antiseptic is undesirable for disinfecting wounds because it causes tissue irritation, painful burning and stinging. Alcohol also precipitates protein which forms a coagulated mass in which bacteria may grew. Rubbing alcohol contain about 70% (BY volume) of ethyl alcohol. It possesses cleansing and lubricant properties and is used as a rubefecient and skin conditioner for bedridden patients. Surgical methylated spirit contain, ethyl alcohol as active constituent for use in hospitals performing surgery and treatment of various patients.

      The term spirit or "Industrial alcohol" is used for brevity and also because it differentiates sharply between alcohol used for beverages or for medicine and alcohol used for technical purposes in the arts, surgical methylated spirit are chemicals of liquid consistency mainly used by surgeons, physicians and other persons in medical profession as an antiseptic measure. Surgical methylated spirit requirement is directly related to the extension of the medical facilities in the country. The provision for medical and health educations increase in the number of beds, clinics, nursing homes etc. demand for surgical methylated spirit is increasing very fast simultaneously.

      Methylated spirits ("metho") is a mixture of ethyl alcohol (95%) and methyl alcohol (5%). The methyl alcohol is poisonous and is added to prevent the methylated spirits being used as cheap drinking alcohol.

      COST ESTIMATION

      Plant Capacity            10,000 Ltr./Day
      Land & Building (2500 sq.mt.)    Rs. 3.48 Cr
      Plant & Machinery                    Rs. 1.50 Cr
      Working Capital for 1 Month    Rs. 1.07 Cr
      Total Capital Investment          Rs. 6.16 Cr
      Rate of Return                          26%
      Break Even Point                      52%

      CONTENTS

      INTRODUCTION
      ETHYL ALCOHOL
      METHYL ALCOHOL
      METHYLATED SPIRITS AS A FUEL
      SAFETY PRECAUTIONS WITH METHO
      NAMES FOR METHYLATED SPIRITS AROUND THE WORLD
      USES AND APPLICATION
      SOME COMMON USES OF SURGICAL SPIRIT ARE:-
      GUIDELINES AND PROCEDURE TO OBTAIN THE REQUIRED LICENCE FOR MANUFACTURING METHYLATED SURGICAL SPIRIT
      GENERAL PROPERTIES
      IT IS DERIVED FROM:
      THE FOLLOWING VARIOUS GRADES ARE AVAILABLE:-
      RAW MATERIALS FOR SURGICAL METHYLATED SPIRIT
      ETHANOL
      METHANOL
      IODOFORM
      METHYL SALICYLATE
      CASTOR OIL
      B.I.S SPECIFICATIONS
      MARKET SURVEY
      PRODUCTION OF SURGICAL METHYLATED SPIRIT IN INDIA
      FORMULATION OF SURGICAL METHYLATED SPIRIT
      FORMULATION-1
      FORMULATION-2
      FORMULATION-3
      PRESENT MANUFACTURERS/SUPPLIERS
      PROCESS OF MANUFACTURE
      PROCESS FLOW SHEET DIAGRAM
      SAFETY DATA SHEET OF SURGICAL METHYLATED SPIRITS
      SECTION 1: IDENTIFICATION OF THE SUBSTANCE OR MIXTURE AND
      OF THE SUPPLIER
      SECTION 2: HAZARDS IDENTIFICATION
      SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS:
      SECTION 4: FIRST AID MEASURES:
      DESCRIPTION OF NECESSARY FIRST AID MEASURES:
      SECTION 5: FIRE FIGHTING MEASURES
      EXTINGUISHING MEDIA & METHODS:
      SECTION 6: ACCIDENTAL RELEASE METHODS
      SECTION 7: HANDLING AND STORAGE
      SUBSECTION 1: HANDLING:
      SUBSECTION 2: STORAGE:
      SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
      SUBSECTION 1: WORKPLACE EXPOSURE GUIDELINES.
      SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
      SECTION 10: STABILITY AND REACTIVITY
      SECTION 11: TOXICOLOGICAL INFORMATION
      ACUTE TOXICITY:
      CHRONIC TOXICITY:
      SECTION 12: ECOLOGICAL INFORMATION
      ECOTOXICITY IN WATER:
      ENVIRONMENTAL RISK PHRASES:
      SECTION 13: DISPOSAL CONSIDERATIONS
      SECTION 14: TRANSPORT INFORMATION
      SECTION 15: REGULATORY INFORMATION
      HSNO CLASSIFICATIONS:
      HSNO CONTROLS:
      TRIGGER QUANTITIES FOR THIS SUBSTANCE BY ITSELF IN A PLACE:
      APPROVED HANDLER TEST CERTIFICATE:
      HAZARDOUS SUBSTANCE LOCATION:
      LOCATION TEST CERTIFICATE:
      HAZARDOUS ATMOSPHERE ZONE:
      HSNO APPROVED CODES OF PRACTICE:
      STANDARD OPERATING PROCEDURE FOR LABORATORY DISINFECTION
      DEFINITIONS:
      PRINCIPLE:
      RISKS:
      PROPER PPE:
      REAGENTS AND SOLUTIONS:
      ALCOHOLS
      GLUTARALDEHYDE
      IODOPHORS
      CHLORINE
      PHENOL
      PROCEDURE:
      NON-ROUTINE DISINFECTION:
      PRINCIPLES OF PLANT LAYOUT
      MAJOR PROVISIONS IN ROAD PLANNING FOR MULTIPURPOSE SERVICE ARE:
      PLANT LOCATION FACTORS
      PRIMARY FACTORS
      1. RAW-MATERIAL SUPPLY:
      2. MARKETS:
      3. POWER AND FUEL SUPPLY:
      4. WATER SUPPLY:
      5. CLIMATE:
      SPECIFIC FACTORS
      6. TRANSPORTATION:
      7. WASTE DISPOSAL:
      8. LABOR:
      9. REGULATORY LAWS:
      10. TAXES:
      11. SITE CHARACTERISTICS:
      12. COMMUNITY FACTORS:
      13. VULNERABILITY TO WARTIME ATTACK:
      14. FLOOD AND FIRE CONTROL:
      EXPLANATION OF TERMS USED IN THE PROJECT REPORT
      1. DEPRECIATION:
      2. FIXED ASSETS:
      3. WORKING CAPITAL:
      4. BREAK-EVEN POINT:
      5. OTHER FIXED EXPENSES:
      6. MARGIN MONEY:
      7. TERM LOANS:
      8. TOTAL LOAD:
      9. LAND AREA/MAN POWER RATIO:
      PLANT LAYOUT
      SUPPLIERS OF RAW MATERIALS
      CASTOR OIL
      METHYL SALICYLATE
      INDUSTRIAL ALCOHOL
      PACKAGING MATERIALS
      LAB TESTING CHEMICALS
      SUPPLIERS OF PLANT AND MACHINERIES
      LABORATORY TESTING EQUIPMENTS
      MATERIAL HANDLING EQUIPMENTS
      BACTERIA PROOF FILTER
      LABELLING MACHINE
      MIXER (GLASS LINED)
      AIR HANDLING UNIT
      DEIONISER
      S.S. STORAGE TANKS
      BOTTLES WASHER

      APPENDIX – A:
      01. PLANT ECONOMICS
      02. LAND & BUILDING
      03. PLANT AND MACHINERY
      04. OTHER FIXED ASSESTS
      05. FIXED CAPITAL
      06. RAW MATERIAL
      07. SALARY AND WAGES
      08. UTILITIES AND OVERHEADS
      09. TOTAL WORKING CAPITAL
      10. TOTAL CAPITAL INVESTMENT
      11. COST OF PRODUCTION
      12. TURN OVER/ANNUM
      13. BREAK EVEN POINT
      14. RESOURCES FOR FINANCE
      15. INSTALMENT PAYABLE IN 5 YEARS
      16. DEPRECIATION CHART FOR 5 YEARS
      17. PROFIT ANALYSIS FOR 5 YEARS
      18. PROJECTED BALANCE SHEET FOR (5 YEARS)

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