Production of L-Lysine Monohydrochloride (100 MT/Day)

PRODUCTION OF L-LYSINE MONOHYDROCHLORIDE

[EIRI/EDPR/4593] J.C. 2810XL

L-Lysine-HCl is an important chemical compound, coming under the category of Amino Acids. It is available in white powder or pale brownish powder and also available in crystalline structure.

It is mainly used in preparation of pharmaceutical products.  It’s use is also extended for food enrichment, Animal feed enrichment, preparation of tissue culture media etc. It is highly demanded all over India.

L-Lysine monohydrochloride is a key amino acid in calcium absorption.

Now a day, its demand is growing day by day, but production is limited. So the demand supply gap is met through import from foreign countries.

L- LysinHCl is the necessary amino acid for the animal but which cannot be synthesized by them. Therefore, it is called the most restrained amino acid L-lysine monohydrochloride is a kind of feed additives which is made from corn starch and other raw materials. The producing of L-lysine monohydrochloride depends on bioengineering principle through the processing of liquid deep-level fermentation and refining.

This product contains a wealth of nutritional amino acid, protein, vitamins, betaine and protein meal. It also contains a large number of inorganic salts which can make the animals to largely assimilate and metabolize protein in the feed, and can intensify and increase the nutrition in the feed, as well as promote digestion and assimilation. At the same time, it has the features of promoting animal’s growth rate, and strengthening abilities of anti-illness. It is the ideal product among the current feed additives, and has been wildly used in different kinds of mixed feed.

COST ESTIMATION

Plant Capacity            100 MT/Day  

Land & Building (24,000 sq.mt.)    Rs. 8.68 Cr    

Plant & Machinery                    Rs. 23.73 Cr 

Working Capital for 2 Months    Rs. 37.49 Cr 

Total Capital Investment          Rs. 70.63 Cr 

Rate of Return                          25%

Break Even Point                      100%

CONTENTS

INTRODUCTION

PRODUCT DESCRIPTION

PROPERTIES

L-LYSINE MONOHYDROCHLORIDE:- 

USES AND APPLICATION

USES OF L-LYSINE:

IN FOOD PRODUCTION

IN BEVERAGE

IN PHARMACEUTICAL

IN HEALTH AND PERSONAL CARE

IN AGRICULTURE/ANIMAL FEED/POULTRY

IN OTHER INDUSTRIES

TABLE. BIOLOGICAL EVALUATION OF AMINO ACID FORTIFICATION OF CEREALS

INCREASE OF PROTEIN EFFICIENCY RATIO (PER) BY SUPPLEMENTATION WITH AMINO ACIDS

BENEFITS OF LYSINE

MARKET POSITION

LIVESTOCK INSIGHTS:

LYSINE HYDROCHLORIDE MARKET: OVERVIEW

LYSINE HYDROCHLORIDE MARKET: DRIVERS & RESTRAINTS

LYSINE HYDROCHLORIDE MARKET: KEY SEGMENTS

LYSINE HYDROCHLORIDE MARKET: REGIONAL OUTLOOK

LYSINE HYDROCHLORIDE MARKET: KEY PLAYERS

PRESENT SUPPLIER/ MANUFACTURERS/COMPETITORS OF AMINO ACIDS

KEY GLOBAL PLAYERS

RAW MATERIALS

MAJOR MARKET PLAYERS IN DIFFERENT GEOGRAPHICAL LOCATIONS

NORTH AMERICA 

EUROPE 

ASIA-PACIFIC

PRODUCTION PROCESS

FIGURE: THE DIAGRAM SHOWS THE PRODUCTION OF L-LYSINE HCI VIA A CONVENTIONAL FERMENTATION PROCESS

FIGURE: THERE HAS BEEN SIGNIFICANT GROWTH RECENTLY IN THE GLOBAL PRODUCTION OF L-LYSINE

(A) INDIRECT FERMENTATION:

(B) DIRECT FERMENTATION:

FIG. CONTROL OF L-LYSINE PRODUCTION FROM CORYNEBACTERIUM GLUTAMICUM

FERMENTATION PROCESS OF L-LYSINE

THIS PROCESS CONSISTS OF FOUR STAGES. THEY ARE:

(I) PREPARATION OF INOCULUM:

THE MEDIUM FOR FIRST SEED CULTURE CONTAINS:

THE MEDIUM FOR SECOND SEED CULTURE CONTAINS:

(I) PREPARATION OF MEDIUM:

(II) FERMENTATION PROCESS:

(III) HARVEST AND RECOVERY:

FERMENTATION PROCESS OF L-LYSINE CAN BE DESCRIBED UNDER FOUR HEADINGS.

(I) INOCULUM PRODUCTION:

(II) PREPARATION OF MEDIUM:

(III) FERMENTATION PROCESS:

(IV) HARVEST AND RECOVERY:

THE PROCESS

FERMENTATION

PRODUCT RECOVERY

PRODUCT CONCENTRATION, DRYING AND PACKAGING

DETAILED PRODUCTION PROCESS

PROCESSING STEPS:-

CHEMICAL REACTION :-

RAW MATERIALS REQUIRE/DAY

PROCESS FLOWSHEET

PLANT LAYOUT

SUPPLIERS OF RAW MATERIALS

SUPPLIERS OF OTHER PLANT AND MACHINERY

STORAGE TANK

AUTOMATIC FILLING & SEALING MACHINES

WEIGHING MACHINES

PACKAGING MACHINE

D.G. SET

LABORATORY TESTING EQUIPMENTS

PRINCIPLES OF PLANT LAYOUT

PLANT LOCATION FACTORS

PRIMARY FACTORS

1. RAW-MATERIAL SUPPLY:

2. MARKETS:

3. POWER AND FUEL SUPPLY:

4. WATER SUPPLY:

5. CLIMATE:

SPECIFIC FACTORS

6. TRANSPORTATION:

A. AVAILABILITY OF VARIOUS SERVICES AND PROJECTED RATES

7. WASTE DISPOSAL:

8. LABOR:

9. REGULATORY LAWS:

10. TAXES:

11. SITE CHARACTERISTICS:

12. COMMUNITY FACTORS:

13. VULNERABILITY TO WARTIME ATTACK:

14. FLOOD AND FIRE CONTROL:

EXPLANATION OF TERMS USED IN THE PROJECT REPORT

1. DEPRECIATION:

2. FIXED ASSETS:

3. WORKING CAPITAL:

4. BREAK-EVEN POINT:

5. OTHER FIXED EXPENSES:

6. MARGIN MONEY:

7. TERM LOANS:

8. TOTAL LOAD:

9. LAND AREA/MAN POWER RATIO:

UTILITIES 

POWER

WORKING 

TOTAL MANPOWER AND PAYROLL 

UTILITIES

WATER

WATER QUALITY PARAMETERS FOR PROCESSED WATER:

STEAM

POWER

EFFLUENT TREATMENT AND DISPOSAL

STANDARDS

TOLERANCE LIMITS FOR INDUSTRIAL EFFLUENT DISCHARGE

WASTE TREATMENT

PRIMARY TREATMENT

ANAEROBIC TREATMENT

ANAEROBIC TREATMENT HAS THE ADVANTAGES OF

SECONDARY TREATMENT

TERTIARY TREATMENT

SOLIDS CONCENTRATION

TYPICAL WASTE SOLIDS CHARACTERISTICS

EQUIPMENT REQUIREMENT 

EQUIPMENT REQUIREMENTS 

PACKAGING TYPES

DOCUMENTS REQUIRED FOR LICENSES 

LIST OF DOCUMENTS:

MACHINERY PHOTOGRTAPH

FINAL PRODUCTS PHOTOGRAPHS

SWOL ANALYSIS

STRENGTHS

OPPORTUNITIES

WEAKNESS

LIMITATIONS

ORGANIZATION CHART

TURNKEY CONSULTANT

IMPLEMENTATION SCHEDULE

APPENDIX – A:

01. PLANT ECONOMICS

02. LAND & BUILDING

03. PLANT AND MACHINERY

04. OTHER FIXED ASSESTS

05. FIXED CAPITAL

06. RAW MATERIAL

07. SALARY AND WAGES

08. UTILITIES AND OVERHEADS

09. TOTAL WORKING CAPITAL

10. TOTAL CAPITAL INVESTMENT

11. COST OF PRODUCTION

12. TURN OVER/ANNUM

13. BREAK EVEN POINT

14. RESOURCES FOR FINANCE

15. INSTALMENT PAYABLE IN 5 YEARS

16. DEPRECIATION CHART FOR 5 YEARS

17. PROFIT ANALYSIS FOR 5 YEARS

18. PROJECTED BALANCE SHEET FOR (5 YEARS)