Industry Overview
Morphine is a powerful opioid analgesic naturally obtained from opium, a dark brown resin produced from the dried latex of the opium poppy (Papaver somniferum). It is primarily used for the management of moderate to severe pain and works directly on the central nervous system to reduce pain perception and alter emotional responses associated with pain. Morphine can be administered through various routes, including oral, sublingual, inhalation, injection, transdermal, and rectal methods. It is widely used for acute and chronic pain conditions, including pain associated with myocardial infarction, kidney stones, and labor.
Repeated administration of morphine may lead to tolerance, physical dependence, and psychological dependence. Potential side effects include respiratory depression, nausea, vomiting, low blood pressure, drowsiness, and constipation. Careful medical supervision is required, particularly during pregnancy and breastfeeding. The primary commercial source of morphine is the isolation of alkaloids from poppy straw. Morphine is also used as a raw material for producing other opioid medicines such as hydromorphone and oxymorphone. It is recognized as an essential medicine by the World Health Organization and is regulated as a controlled substance in various countries.
Cost Estimation
| Particulars | Details |
|---|---|
| Poppy Straw Processing | 80 Tons/Day |
| Morphine Content | 0.7% |
| Yield | 0.56% |
| Plant Capacity | 448 KG/Day |
| Land & Building (10,000 sq.mt.) | Rs. 5.50 Cr |
| Plant & Machinery | Rs. 8.00 Cr |
| Working Capital for 2 Month | Rs. 84.46 Cr |
| Total Capital Investment | Rs. 98.66 Cr |
| Rate of Return | 32% |
| Break Even Point | 36% |
Content Index
- INTRODUCTION
- USES AND APPLICATION OF MORPHINE
- MEDICAL USES
- PAIN
- SHORTNESS OF BREATH
- PROPERTIES AND PHARMACOLOGY
- PHARMACOLOGY
- PHARMACODYNAMICS
- MORPHINE AT OPIOID RECEPTORS
- EQUIANALGESIC DOSES
- MORPHINE HYDROCHLORIDE AMPOULE FOR VETERINARY USE
- GENE EXPRESSION
- EFFECTS ON THE IMMUNE SYSTEM
- NATURAL OCCURRENCE
- CONCENTRATED POPPY STRAW
- FORMING CPS FROM POPPY STRAW:
- ALKALOIDS COMPOSITION:
- ADVANTAGES OF CPS (CONCENTRATED POPPY STRAW)
- ADVANTAGES OF CPS:
- CHALLENGES:
- CPS: A WAY FORWARD
- OPIUM POPPY PLANT
- OPIUM POPPY GROWING AREAS
- MORPHINE EXTRACTION FROM CONCENTRATE POPPY STRAW
- MARKET OVERVIEW OF MORPHINE
- MORPHINE OVERVIEW
- MORPHINE MARKET LEADERS
- MORPHINE FROM OPIUM
- FIGURE: MORPHINE EXTRACTION PROCESS
- FIGURE: PROCESS OF ACETYLATION OF MORPHINE
- MANUFACTURING PROCESS OF MORPHINE FROM POPPY MEAL
- RAW MATERIALS
- PROCESS FLOW DIAGRAM OF MORPHINE FROM POPPY STRAW
- PRINCIPLES OF PLANT LAYOUT
- STORAGE LAYOUT:
- EQUIPMENT LAYOUT:
- SAFETY:
- PLANT EXPANSION:
- FLOOR SPACE:
- UTILITIES SERVICING:
- BUILDING:
- MATERIAL-HANDLING EQUIPMENT:
- RAILROADS AND ROADS:
- MAJOR PROVISIONS IN ROAD PLANNING FOR MULTIPURPOSE SERVICE ARE:
- PLANT LOCATION FACTORS
- PRIMARY FACTORS
- SPECIFIC FACTORS
- EXPLANATION OF TERMS USED IN THE PROJECT REPORT
- PROJECT IMPLEMENTATION SCHEDULES
- PROJECT HANDLING
- PROJECT SCHEDULING
- PROJECT CONSTRUCTION SCHEDULE
- TIME SCHEDULE
- ADDRESSES OF PLANT AND MACHINERY SUPPLIERS
Appendix
- APPENDIX – A:
- 01. PLANT ECONOMICS
- 02. LAND & BUILDING
- 03. PLANT AND MACHINERY
- 04. OTHER FIXED ASSETS
- 05. FIXED CAPITAL
- 06. RAW MATERIAL
- 07. SALARY AND WAGES
- 08. UTILITIES AND OVERHEADS
- 09. TOTAL WORKING CAPITAL
- 10. TOTAL CAPITAL INVESTMENT
- 11. COST OF PRODUCTION
- 12. TURN OVER/ANNUM
- 13. BREAK EVEN POINT
- 14. RESOURCES FOR FINANCE
- 15. INSTALMENT PAYABLE IN 5 YEARS
- 16. DEPRECIATION CHART FOR 5 YEARS
- 17. PROFIT ANALYSIS FOR 5 YEARS
- 18. PROJECTED BALANCE SHEET FOR (5 YEARS)
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